http://emedicine.medscape.com/article/1923077-overview
The baroreflex system is the system that helps to regulate function of the heart, kidneys, and peripheral vasculature to maintain an appropriate blood pressure. The carotid sinus baroreflex activation device is currently the only medical device used to treat refractory hypertension. It consists of an implantable pulse generator, bilateral carotid sinus leads, and a computer programming system. The pulse generator is placed in a subcutaneous pocket in the pectoral region below the collar bone. Electrodes are placed bilaterally on the carotid arteries (two main blood pressure control points), and the leads run under the skin and connect to the pulse generator. Placement of the leads is determined by intraoperative blood pressure responses to test activations. The programming system regulates the activation energy from the device to the leads and can be adjusted based on the needs of the patient.
When the device is activated, the programming system delivers activation energy through the leads to the carotid sinus. The baroreceptors of the carotid arteries send signals through neural pathways to the brain that there is a rise in blood pressure that needs to be corrected. The brain sends signals to other parts of the body to counteract the rise in blood pressure by modulating the nervous system and hormones to dilate blood vessels and allow blood to flow more freely, reduce the heart rate, and influence fluid handling by the kidneys. This results in reduced blood pressure and workload by the heart, improved circulation, and a more optimal neurohormonal balance.
Trích bài học lớp Beginning Coding
http://hs3m.cypresscollege.edu/3mhis/wcrs/reference2/index.html?file=fb.ref
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